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Target
Dipeptidyl peptidase 1
Ligand
BDBM50147182
Substrate
n/a
Meas. Tech.
ChEBML_44964
Ki
40000±n/a nM
Citation
 Mucha, A; Pawel, M; Hurek, J; Kafarski, P Synthesis and activity of phosphinic tripeptide inhibitors of cathepsin C. Bioorg Med Chem Lett 14:3113-6 (2004) [PubMed]  Article 
Target
Name:
Dipeptidyl peptidase 1
Synonyms:
CATC_MOUSE | Ctsc | Dipeptidyl peptidase I
Type:
PROTEIN
Mol. Mass.:
52379.83
Organism:
Mus musculus
Description:
ChEMBL_44964
Residue:
462
Sequence:
MGPWTHSLRAVLLLVLLGVCTVRSDTPANCTYPDLLGTWVFQVGPRSSRSDINCSVMEATEEKVVVHLKKLDTAYDELGNSGHFTLIYNQGFEIVLNDYKWFAFFKYEVRGHTAISYCHETMTGWVHDVLGRNWACFVGKKVESHIEKVNMNAAHLGGLQERYSERLYTHNHNFVKAINTVQKSWTATAYKEYEKMSLRDLIRRSGHSQRIPRPKPAPMTDEIQQQILNLPESWDWRNVQGVNYVSPVRNQESCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEESCFPYTAKDSPCKPRENCLRYYSSDYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGRDPVTGIEYWIIKNSWGSNWGESGYFRIRRGTDECAIESIAVAAIPIPKL
  
Inhibitor
Name:
BDBM50147182
Synonyms:
3-{[1-(2-Amino-acetylamino)-3-methyl-butyl]-hydroxy-phosphinoyl}-propionic acid methyl ester; hydrochloride | CHEMBL552706
Type:
Small organic molecule
Emp. Form.:
C11H23N2O5P
Mol. Mass.:
294.2845
SMILES:
COC(=O)CCP(O)(=O)C(CC(C)C)NC(=O)CN
Structure:
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