Reaction Details Report a problem with these data
Target
Glutathione hydrolase 1 proenzyme
Ligand
BDBM50148336
Substrate
n/a
Meas. Tech.
ChEBML_68880
pH
8±n/a
Ki
520000±n/a nM
Comments
extracted
Citation
 Lherbet, C; Gravel, C; Keillor, JW Synthesis of S-alkyl L-homocysteine analogues of glutathione and their kinetic studies with gamma-glutamyl transpeptidase. Bioorg Med Chem Lett 14:3451-5 (2004) [PubMed]  Article 
Target
Name:
Glutathione hydrolase 1 proenzyme
Synonyms:
GGT1_RAT | Gamma-glutamyltranspeptidase 1 | Ggt | Ggt1
Type:
PROTEIN
Mol. Mass.:
61615.37
Organism:
Rattus norvegicus
Description:
ChEMBL_68879
Residue:
568
Sequence:
MKNRFLVLGLVAVVLVFVIIGLCIWLPTTSGKPDHVYSRAAVATDAKRCSEIGRDMLQEGGSVVDAAIASLLCMGLINAHSMGIGGGLFFTIYNSTTRKAEVINAREMAPRLANTSMFNNSKDSEEGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARHGFPVGKGLARALDKKRDIIEKTPALCEVFCRQGKVLQEGETVTMPKLADTLQILAQEGARAFYNGSLTAQIVKDIQEAGGIMTVEDLNNYRAEVIEHPMSIGLGDSTLYVPSAPLSGPVLILILNILKGYNFSPKSVATPEQKALTYHRIVEAFRFAYAKRTMLGDPKFVDVSQVIRNMSSEFYATQLRARITDETTHPTAYYEPEFYLPDDGGTAHLSVVSEDGSAVAATSTINLYFGSKVLSRVSGILFNDEMDDFSSPNFTNQFGVAPSPANFIKPGKQPLSSMCPSIIVDKDGKVRMVVGASGGTQITTSVALAIINSLWFGYDVKRAVEEPRLHNQLLPNTTTVEKNIDQVVTAGLKTRHHHTEVTPDFIAVVQAVVRTSGGWAAASDSRKGGEPAGY
  
Inhibitor
Name:
BDBM50148336
Synonyms:
(1S)-1-carboxy-3-({2-[(carboxymethyl)amino]-2-oxoethyl}thio)propan-1-aminium chloride | CHEMBL177381
Type:
Small organic molecule
Emp. Form.:
C9H17N2O5S
Mol. Mass.:
265.306
SMILES:
[NH3+][C@@H](CCSCCC(=O)NCC(O)=O)C(O)=O
Structure:
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