Reaction Details Report a problem with these data
Target
Beta-glucuronidase
Ligand
BDBM50142193
Substrate
n/a
Meas. Tech.
ChEBML_37581
IC50
>30000±n/a nM
Citation
 Ko, HH; Weng, JR; Tsao, LT; Yen, MH; Wang, JP; Lin, CN Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica. Bioorg Med Chem Lett 14:1011-4 (2004) [PubMed]  Article 
Target
Name:
Beta-glucuronidase
Synonyms:
BGLR_RAT | Gus | Gusb
Type:
PROTEIN
Mol. Mass.:
74794.72
Organism:
Rattus norvegicus
Description:
ChEMBL_37581
Residue:
648
Sequence:
MSPRRSVCWFVLGQLLCSCAVALQGGMLFPKETPSRELKVLDGLWSFRADYSNNRLQGFEKQWYRQPLRESGPTLDMPVPSSFNDITQEAELRNFIGWVWYEREAVLPQRWTQDTDRRVVLRINSAHYYAVVWVNGIHVVEHEGGHLPFEADITKLVQSGPLTTFRVTIAINNTLTPYTLPPGTIVYKTDPSMYPKGYFVQDISFDFFNYAGLHRSVVLYTTPTTYIDDITVTTDVDRDVGLVNYWISVQGSDHFQLEVRLLDEDGKIVARGTGNEGQLKVPRAHLWWPYLMHEHPAYLYSLEVTMTTPESVSDFYTLPVGIRTVAVTKSKFLINGKPFYFQGVNKHEDSDIRGRGFDWPLLIKDFNLLRWLGANSFRTSHYPYSEEVLQLCDRYGIVVIDECPGVGIVLPQSFGNVSLRHHLEVMDELVRRDKNHPAVVMWSVANEPVSSLKPAGYYFKTLIAHTKALDPTRPVTFVSNTRYDADMGAPYVDVICVNSYLSWYHDYGHLEVIQLQLTSQFENWYKMYQKPIIQSEYGADAVSGLHEDPPRMFSEEYQTALLENYHLILDEKRKEYVIGELIWNFADFMTNQSPLRVTGNKKGIFTRQRNPKMAAFILRERYWRIANETRGYGSVPRTQCMGSRPFTF
  
Inhibitor
Name:
BDBM50142193
Synonyms:
2'-hydroxydaidzein | 3-(2,4-dihydroxyphenyl)-7-hydroxy-4H-1-benzopyran-4-one | 3-(2,4-dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one | 4H-1-benzopyran-4-one, 3-(2,4-dihydroxyphenyl)-7-hydroxy- | CHEMBL6694
Type:
Small organic molecule
Emp. Form.:
C15H10O5
Mol. Mass.:
270.2369
SMILES:
Oc1ccc(c(O)c1)-c1coc2cc(O)ccc2c1=O
Structure:
Search PDB for entries with ligand similarity: