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Target
Beta-glucuronidase
Ligand
BDBM50142192
Substrate
n/a
Meas. Tech.
ChEBML_37581
IC50
5900±n/a nM
Citation
 Ko, HH; Weng, JR; Tsao, LT; Yen, MH; Wang, JP; Lin, CN Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica. Bioorg Med Chem Lett 14:1011-4 (2004) [PubMed]  Article 
Target
Name:
Beta-glucuronidase
Synonyms:
BGLR_RAT | Gus | Gusb
Type:
PROTEIN
Mol. Mass.:
74794.72
Organism:
Rattus norvegicus
Description:
ChEMBL_37581
Residue:
648
Sequence:
MSPRRSVCWFVLGQLLCSCAVALQGGMLFPKETPSRELKVLDGLWSFRADYSNNRLQGFEKQWYRQPLRESGPTLDMPVPSSFNDITQEAELRNFIGWVWYEREAVLPQRWTQDTDRRVVLRINSAHYYAVVWVNGIHVVEHEGGHLPFEADITKLVQSGPLTTFRVTIAINNTLTPYTLPPGTIVYKTDPSMYPKGYFVQDISFDFFNYAGLHRSVVLYTTPTTYIDDITVTTDVDRDVGLVNYWISVQGSDHFQLEVRLLDEDGKIVARGTGNEGQLKVPRAHLWWPYLMHEHPAYLYSLEVTMTTPESVSDFYTLPVGIRTVAVTKSKFLINGKPFYFQGVNKHEDSDIRGRGFDWPLLIKDFNLLRWLGANSFRTSHYPYSEEVLQLCDRYGIVVIDECPGVGIVLPQSFGNVSLRHHLEVMDELVRRDKNHPAVVMWSVANEPVSSLKPAGYYFKTLIAHTKALDPTRPVTFVSNTRYDADMGAPYVDVICVNSYLSWYHDYGHLEVIQLQLTSQFENWYKMYQKPIIQSEYGADAVSGLHEDPPRMFSEEYQTALLENYHLILDEKRKEYVIGELIWNFADFMTNQSPLRVTGNKKGIFTRQRNPKMAAFILRERYWRIANETRGYGSVPRTQCMGSRPFTF
  
Inhibitor
Name:
BDBM50142192
Synonyms:
3-(2,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-one | CHEMBL6665
Type:
Small organic molecule
Emp. Form.:
C15H10O6
Mol. Mass.:
286.2363
SMILES:
Oc1ccc(c(O)c1)-c1coc2cc(O)cc(O)c2c1=O
Structure:
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