Reaction Details Report a problem with these data
Target
Cytidine deaminase
Ligand
BDBM50366986
Substrate
n/a
Meas. Tech.
ChEMBL_52528 (CHEMBL665300)
Ki
300±n/a nM
Citation
 Marquez, VE; Liu, PS; Kelley, JA; Driscoll, JS; McCormack, JJ Synthesis of 1,3-diazepin-2-one nucleosides as transition-state inhibitors of cytidine deaminase. J Med Chem 23:713-5 (1980) [PubMed]  Article 
Target
Name:
Cytidine deaminase
Synonyms:
CDD_MOUSE | Cda | Cdd | Cytidine aminohydrolase
Type:
PROTEIN
Mol. Mass.:
16129.75
Organism:
Mus musculus
Description:
ChEMBL_52531
Residue:
146
Sequence:
MAQERPSCAVEPEHVQRLLLSSREAKKSAYCPYSRFPVGAALLTGDGRIFSGCNIENACYPLGVCAERTAIQKAISEGYKDFRAIAISSDLQEEFISPCGACRQVMREFGTDWAVYMTKPDGTFVVRTVQELLPASFGPEDLQKIQ
  
Inhibitor
Name:
BDBM50366986
Synonyms:
CHEMBL607779
Type:
Small organic molecule
Emp. Form.:
C10H18N2O5
Mol. Mass.:
246.2603
SMILES:
OC[C@H]1OC([C@H](O)[C@@H]1O)N1CCCCNC1=O |r|
Structure:
Search PDB for entries with ligand similarity: