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Target
Beta-2 adrenergic receptor
Ligand
BDBM50026853
Substrate
n/a
Meas. Tech.
ChEBML_37821
IC50
25±n/a nM
Citation
 Baldwin, JJ; McClure, DE; Gross, DM; Williams, M Use of (S)-(trifloxymethyl)oxirane in the synthesis of a chiral beta-adrenoceptor antagonist, (R)- and (S)-9-[[3-(tert-butylamino)-2-hydroxypropyl]oximino]fluorene. J Med Chem 25:931-6 (1982) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2_BOVIN | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor | adrenergic Beta
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47141.18
Organism:
BOVINE
Description:
adrenergic Beta ADRB2 BOVINE::Q28044
Residue:
418
Sequence:
MGQPGNRSVFLLAPNASHAPDQNVTLERDEAWVVGMGILMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGACHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYLAITSPFKYQCLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRASHKEAINCYAKETCCDFFTNQPYAIASSIVSFYLPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNVSQVEQDGRSGLGQRRTSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIKDNLIRKEIYILLNWLGYINSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGCSSNSNDRTDYTGEQSGYHLGEEKDSELLCEDPPGTENFVNQQGTVPSDSIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50026853
Synonyms:
CHEMBL368457 | Fluoren-9-one O-(3-tert-butylamino-2-hydroxy-propyl)-oxime
Type:
Small organic molecule
Emp. Form.:
C20H24N2O2
Mol. Mass.:
324.4168
SMILES:
[#6]C([#6])([#6])[#7]-[#6]-[#6](-[#8])-[#6]-[#8]\[#7]=[#6]-1\c2ccccc2-c2ccccc-12
Structure:
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