Reaction Details Report a problem with these data
Target
Muscarinic receptor M1
Ligand
BDBM50367741
Substrate
n/a
Meas. Tech.
ChEBML_140160
Ki
5.2±n/a nM
Citation
 Rzeszotarski, WJ; McPherson, DW; Ferkany, JW; Kinnier, WJ; Noronha-Blob, L; Kirkien-Rzeszotarski, A Affinity and selectivity of the optical isomers of 3-quinuclidinyl benzilate and related muscarinic antagonists. J Med Chem 31:1463-6 (1988) [PubMed]  Article 
Target
Name:
Muscarinic receptor M1
Synonyms:
Muscarinic acetylcholine receptor M1
Type:
PROTEIN
Mol. Mass.:
15022.43
Organism:
Bos taurus
Description:
ChEMBL_140161
Residue:
139
Sequence:
ETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRTPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPAKQPPRSSPNTVKRPTRKGRERAGKGQKPRGKEQLAKR
  
Inhibitor
Name:
BDBM50367741
Synonyms:
CHEMBL1788286
Type:
Small organic molecule
Emp. Form.:
C21H21NO3
Mol. Mass.:
335.3963
SMILES:
O=C(O[C@@H]1CN2CCC1CC2)C1c2ccccc2Oc2ccccc12 |r,wU:3.2,TLB:2:3:7.6:9.10,(5.68,-6.55,;5.7,-5.33,;7.04,-4.57,;8.59,-4.57,;8.54,-5.86,;9.9,-4.81,;8.96,-3.17,;10.01,-2.65,;9.93,-3.78,;11.26,-4.56,;11.3,-5.75,;4.37,-4.56,;3.61,-5.89,;4.37,-7.23,;3.62,-8.56,;2.07,-8.57,;1.3,-7.23,;2.07,-5.91,;1.27,-4.57,;2.05,-3.22,;1.27,-1.9,;2.02,-.55,;3.57,-.55,;4.35,-1.88,;3.6,-3.22,)|
Structure:
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