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Target
Adenosylhomocysteinase
Ligand
BDBM50011148
Substrate
n/a
Meas. Tech.
ChEBML_197203
Ki
125±n/a nM
Citation
 Borcherding, DR; Narayanan, S; Hasobe, M; McKee, JG; Keller, BT; Borchardt, RT Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 11. Molecular dissections of neplanocin A as potential inhibitors of S-adenosylhomocysteine hydrolase. J Med Chem 31:1729-38 (1988) [PubMed]  Article 
Target
Name:
Adenosylhomocysteinase
Synonyms:
Adenosylhomocysteinase | SAHH_HUMAN | AHCY | SAHH
Type:
PROTEIN
Mol. Mass.:
47714.06
Organism:
Human
Description:
ChEMBL_1507791
Residue:
432
Sequence:
MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY
  
Inhibitor
Name:
BDBM50011148
Synonyms:
CHEMBL45537 | 4-(6-Amino-purin-9-yl)-but-2-en-1-ol | (Z)-4-(6-Amino-purin-9-yl)-but-2-en-1-ol
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
Nc1ncnc2n(C\C=C/CO)cnc12
Structure:
Search PDB for entries with ligand similarity: