Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50367882
Substrate
n/a
Meas. Tech.
ChEMBL_29632 (CHEMBL639739)
Ki
18400±n/a nM
Citation
 Trivedi, BK; Bruns, RF C2,N6-disubstituted adenosines: synthesis and structure-activity relationships. J Med Chem 32:1667-73 (1989) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50367882
Synonyms:
CHEMBL605238
Type:
Small organic molecule
Emp. Form.:
C20H25N7O4
Mol. Mass.:
427.457
SMILES:
OC[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(NN3CCCC3)nc(Nc3ccccc3)nc12 |r|
Structure:
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