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Target
Sex hormone-binding globulin
Ligand
BDBM50367916
Substrate
n/a
Meas. Tech.
ChEBML_35818
IC50
3.7±n/a nM
Citation
 Winneker, RC; Wagner, MM; Singh, B A novel, nonsteroidal inhibitor of androgen binding to the rat androgen binding protein: diethyl [[[3-(2,6-dimethyl-4-pyridinyl)-4-fluorophenyl]amino]methylene] propanedioate. J Med Chem 33:129-32 (1990) [PubMed]  Article 
Target
Name:
Sex hormone-binding globulin
Synonyms:
ABP | SBP | SHBG_RAT | Sex hormone-binding globulin | Sex steroid-binding protein | Shbg | Testis-specific androgen-binding protein
Type:
PROTEIN
Mol. Mass.:
44530.46
Organism:
Rattus norvegicus
Description:
ChEMBL_35819
Residue:
403
Sequence:
MEKGEVASLRCRLLLLLLLLTLPPTHQGRTLRHIDPIQSAQDSPAKYLSNGPGQEPVTVLTIDLTKISKPSSSFEFRTWDPEGVIFYGDTNTEDDWFMLGLRDGQLEIQLHNLWARLTVGFGPRLNDGRWHPVELKMNGDSLLLWVDGKEMLCLRQVSASLADHPQLSMRIALGGLLLPTSKLRFPLVPALDGCIRRDIWLGHQAQLSTSARTSLGNCDVDLQPGLFFPPGTHAEFSLQDIPQPHTDPWTFSLELGFKLVDGAGRLLTLGTGTNSSWLTLHLQDQTVVLSSEAEPKLALPLAVGLPLQLKLDVFKVALSQGPKMEVLSTSLLRLASLWRLWSHPQGHLSLGALPGEDSSASFCLSDLWVQGQRLDIDKALSRSQDIWTHSCPQSPSNDTHTSH
  
Inhibitor
Name:
BDBM50367916
Synonyms:
METHYLTRIENOLONE | Metribolone | R-1881
Type:
Small organic molecule
Emp. Form.:
C19H24O2
Mol. Mass.:
284.3927
SMILES:
C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3C=C[C@]12C |r,c:16,19,t:9|
Structure:
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