Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50004568
Substrate
n/a
Meas. Tech.
ChEBML_29421
Ki
11±n/a nM
Citation
 Suzuki, F; Shimada, J; Mizumoto, H; Karasawa, A; Kubo, K; Nonaka, H; Ishii, A; Kawakita, T Adenosine A1 antagonists. 2. Structure-activity relationships on diuretic activities and protective effects against acute renal failure. J Med Chem 35:3066-75 (1992) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor | AA1R_CAVPO | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor | Adenosine Receptor A1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36501.39
Organism:
GUINEA PIG
Description:
ADENOSINE A1 ADORA1 GUINEA PIG::P47745
Residue:
326
Sequence:
MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD
  
Inhibitor
Name:
BDBM50004568
Synonyms:
8-Cyclohexylmethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione | 8-Cyclohexylmethyl-1,3-dipropyl-3,9-dihydro-purine-2,6-dione | CHEMBL160704
Type:
Small organic molecule
Emp. Form.:
C18H28N4O2
Mol. Mass.:
332.4405
SMILES:
CCCn1c2nc(CC3CCCCC3)[nH]c2c(=O)n(CCC)c1=O
Structure:
Search PDB for entries with ligand similarity: