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Target
D(2) dopamine receptor
Ligand
BDBM50019742
Substrate
n/a
Meas. Tech.
ChEBML_58197
IC50
>10000±n/a nM
Citation
 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK Novel piperidine sigma receptor ligands as potential antipsychotic drugs. J Med Chem 35:4344-61 (1992) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2_MOUSE | Dopamine D2 receptor | Dopamine Receptor D2 | Drd2
Type:
Enzyme
Mol. Mass.:
50957.64
Organism:
Mus musculus (Mouse)
Description:
P61168
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50019742
Synonyms:
9-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)-9H-carbazole | 9-(3-(3,5-dimethylpiperazin-1-yl)propyl)-9H-carbazole | 9-[3-((3R,5R)-3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole | 9-[3-((3R,5S)-3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole | 9-[3-((3S,5R)-3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole | 9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole | 9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole (Rimcazole) (BW234U) | 9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole(rimcazole) | CHEMBL275707 | RIMCAZOLE
Type:
Small organic molecule
Emp. Form.:
C21H27N3
Mol. Mass.:
321.4592
SMILES:
C[C@H]1CN(CCCn2c3ccccc3c3ccccc23)C[C@@H](C)N1 |r|
Structure:
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