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Target
Inositol polyphosphate-5-phosphatase A
Ligand
BDBM50407004
Substrate
n/a
Meas. Tech.
ChEBML_4316
Ki
>100000000±n/a nM
Citation
 Kozikowski, AP; Ognyanov, VI; Chen, C; Fauq, AH; Safrany, ST; Wilcox, RA; Nahorski, SR Deoxygenated inositol 1,4,5-trisphosphate analogues and their interaction with metabolic enzymes. (1R,2R,4R)-cyclohexane-1,2,4-tris(methylenesulfonate): a potent selective 5-phosphatase inhibitor. J Med Chem 36:3035-8 (1993) [PubMed]  Article 
Target
Name:
Inositol polyphosphate-5-phosphatase A
Synonyms:
5PTASE | I5P1_HUMAN | INPP5A | Type I inositol-1,4,5-trisphosphate 5-phosphatase
Type:
PROTEIN
Mol. Mass.:
47823.52
Organism:
Homo sapiens (Human)
Description:
ChEMBL_4316
Residue:
412
Sequence:
MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVVHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVYLDENYKSQEHFTALGSFYFLHESLKNIYQFDFKAKKYRKVAGKEIYSDTLESTPMLEKEKFPQDYFPECKWSRKGFIRTRWCIADCAFDLVNIHLFHDASNLVAWETSPSVYSGIRHKALGYVLDRIIDQRFEKVSYFVFGDFNFRLDSKSVVETLCTKATMQTVRAADTNEVVKLIFRESDNDRKVMLQLEKKLFDYFNQEVFRDNNGTALLEFDKELSVFKDRLYELDISFPPSYPYSEDARQGEQYMNTRCPAWCDRILMSPSAKELVLRSESEEKVVTYDHIGPNVCMGDHKPVFLAFRIMPGAGKPHAHVHKCCVVQ
  
Inhibitor
Name:
BDBM50407004
Synonyms:
CHEMBL2092922
Type:
Small organic molecule
Emp. Form.:
C9H18O9S3
Mol. Mass.:
366.429
SMILES:
OS(=O)(=O)C[C@H]1CCC(CS(O)(=O)=O)[C@H](CS(O)(=O)=O)C1 |r|
Structure:
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