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Target
Platelet-activating factor receptor
Ligand
BDBM50038749
Substrate
n/a
Meas. Tech.
ChEMBL_151699 (CHEMBL760448)
Ki
1.6±n/a nM
Citation
 Sheppard, GS; Pireh, D; Carrera, GM; Bures, MG; Heyman, HR; Steinman, DH; Davidsen, SK; Phillips, JG; Guinn, DE; May, PD 3-(2-(3-Pyridinyl)thiazolidin-4-oyl)indoles, a novel series of platelet activating factor antagonists. J Med Chem 37:2011-32 (1994) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50038749
Synonyms:
(R)-2-Pyridin-3-yl-thiazolidine-4-carboxylic acid [3-(3,4,5-trimethoxy-benzoyl)-phenyl]-amide | CHEMBL439937
Type:
Small organic molecule
Emp. Form.:
C25H25N3O5S
Mol. Mass.:
479.548
SMILES:
COc1cc(cc(OC)c1OC)C(=O)c1cccc(NC(=O)[C@@H]2CSC(N2)c2cccnc2)c1
Structure:
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