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Target
Somatostatin receptor type 2
Ligand
BDBM50068053
Substrate
n/a
Meas. Tech.
ChEMBL_200367 (CHEMBL805715)
Ki
830±n/a nM
Citation
 Liu, S; Tang, C; Ho, B; Ankersen, M; Stidsen, CE; Crider, AM Nonpeptide somatostatin agonists with sst4 selectivity: synthesis and structure-activity relationships of thioureas. J Med Chem 41:4693-705 (1998) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2)
Type:
Enzyme
Mol. Mass.:
41344.94
Organism:
Homo sapiens (Human)
Description:
P30874
Residue:
369
Sequence:
MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM50068053
Synonyms:
1-(4-Amino-butyl)-3-{3-[(5-bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)-amino]-propyl}-thiourea | CHEMBL145472
Type:
Small organic molecule
Emp. Form.:
C20H26BrCl2N5S
Mol. Mass.:
519.329
SMILES:
NCCCCNC(=S)NCCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1
Structure:
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