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Target
Delta-type opioid receptor
Ligand
BDBM50369520
Substrate
n/a
Meas. Tech.
ChEMBL_147149 (CHEMBL758174)
Ki
150±n/a nM
Citation
 Neumeyer, JL; Bidlack, JM; Zong, R; Bakthavachalam, V; Gao, P; Cohen, DJ; Negus, SS; Mello, NK Synthesis and opioid receptor affinity of morphinan and benzomorphan derivatives: mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine dependence. J Med Chem 43:114-22 (2000) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50369520
Synonyms:
CHEMBL1202425
Type:
Small organic molecule
Emp. Form.:
C20H25NO2
Mol. Mass.:
311.418
SMILES:
Oc1ccc2C(=O)C3C4CCCCC4(CCN3CC3CC3)c2c1 |TLB:6:5:8:14.15.16,22:21:8:14.15.16,THB:17:16:8:4.5.21,9:8:14.15.16:4.5.21|
Structure:
Search PDB for entries with ligand similarity: