Reaction Details Report a problem with these data
Target
Gamma-aminobutyric acid receptor subunit rho-2
Ligand
BDBM23183
Substrate
n/a
Meas. Tech.
ChEMBL_68581 (CHEMBL679668)
Kd
1400±n/a nM
Citation
 Chebib, M; Johnston, GA GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology. J Med Chem 43:1427-47 (2000) [PubMed]  Article 
Target
Name:
Gamma-aminobutyric acid receptor subunit rho-2
Synonyms:
GABA receptor rho-2 subunit | GABA(A) receptor subunit rho-2 | GABA(C) receptor | GABA-C receptor | GABRR2 | GBRR2_HUMAN | Gamma-aminobutyric acid receptor subunit rho-2
Type:
PROTEIN
Mol. Mass.:
54168.90
Organism:
Homo sapiens (Human)
Description:
ChEMBL_68702
Residue:
465
Sequence:
MPYFTRLILFLFCLMVLVESRKPKRKRWTGQVEMPKPSHLYKKNLDVTKIRKGKPQQLLRVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLREKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVFS
  
Inhibitor
Name:
BDBM23183
Synonyms:
5-(aminomethyl)-1,2-oxazol-3-ol | Agarin | CHEMBL273481 | Muscimol | Pantherine
Type:
GABA Agonist
Emp. Form.:
C4H6N2O2
Mol. Mass.:
114.1026
SMILES:
NCc1cc(=O)[nH]o1
Structure:
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