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Target
Peptidyl-prolyl cis-trans isomerase A
Ligand
BDBM50102555
Substrate
n/a
Meas. Tech.
ChEMBL_51873 (CHEMBL666528)
Kd
4700±n/a nM
Citation
 Wang, HC; Kim, K; Bakhtiar, R; Germanas, JP Structure-activity studies of ground- and transition-state analogue inhibitors of cyclophilin. J Med Chem 44:2593-600 (2001) [PubMed]  Article 
Target
Name:
Peptidyl-prolyl cis-trans isomerase A
Synonyms:
CYPA | CYPA PPIase | Cyclophilin A | Cyclosporin A-binding protein | PPIA | PPIA_HUMAN | PPIase A | Peptidyl-prolyl cis-trans isomerase A | Rotamase A
Type:
Protein
Mol. Mass.:
18015.32
Organism:
Homo sapiens (Human)
Description:
P62937
Residue:
165
Sequence:
MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE
  
Inhibitor
Name:
BDBM50102555
Synonyms:
6-Benzyloxycarbonylamino-6-naphthalen-2-ylmethyl-5-oxo-hexahydro-indolizine-8a-carboxylic acid methyl ester | CHEMBL313327
Type:
Small organic molecule
Emp. Form.:
C29H30N2O5
Mol. Mass.:
486.5589
SMILES:
COC(=O)[C@]12CCCN1C(=O)[C@@](Cc1ccc3ccccc3c1)(CC2)NC(=O)OCc1ccccc1
Structure:
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