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Target
Chymotrypsin-C
Ligand
BDBM50111591
Substrate
n/a
Meas. Tech.
ChEMBL_49925 (CHEMBL664294)
IC50
100000±n/a nM
Citation
 McGovern, SL; Caselli, E; Grigorieff, N; Shoichet, BK A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening. J Med Chem 45:1712-22 (2002) [PubMed]  Article 
Target
Name:
Chymotrypsin-C
Synonyms:
CLCR | CTRC | CTRC_HUMAN | Caldecrin | Chymotrypsin | Chymotrypsin C | Chymotrypsin-C
Type:
Enzyme
Mol. Mass.:
29487.98
Organism:
Homo sapiens (Human)
Description:
Q99895
Residue:
268
Sequence:
MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
  
Inhibitor
Name:
BDBM50111591
Synonyms:
4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benzene-1,2-diol | CHEMBL34034
Type:
Small organic molecule
Emp. Form.:
C15H10F2N2O2S
Mol. Mass.:
320.314
SMILES:
Oc1ccc(cc1O)-c1csc(Nc2ccc(F)cc2F)n1
Structure:
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