Reaction Details Report a problem with these data
Target
Carbonic anhydrase 4
Ligand
BDBM50152965
Substrate
n/a
Meas. Tech.
ChEMBL_302422 (CHEMBL828825)
Ki
30000±n/a nM
Citation
 Innocenti, A; Zimmerman, S; Ferry, JG; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the methanoarchaeon Methanobacterium thermoautotrophicum (Cab) with anions. Bioorg Med Chem Lett 14:4563-7 (2004) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 4
Synonyms:
CA-IV | CA4 | CAH4_HUMAN | Carbonate dehydratase IV | Carbonic anhydrase | Carbonic anhydrase 4 (CA IV) | Carbonic anhydrase IV (CA IV)
Type:
Enzyme
Mol. Mass.:
35037.98
Organism:
Homo sapiens (Human)
Description:
P22748
Residue:
312
Sequence:
MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLGPMLACLLAGFLR
  
Inhibitor
Name:
BDBM50152965
Synonyms:
(methylidyneammoniumyl)oxidanide | CHEMBL185198 | H-C#NO | HCNO | Knallsaeure | [C(H)NO] | [CH(NO)] | formonitrile oxideformonitrile-N-oxidehydrido(nitrosyl-kappaN)carbonhydrido(oxidonitrato-N)carbon | fulminic acid | hydrogen cyanide N-oxide | methylidyne(oxo)-lambda(5)-azane
Type:
Small organic molecule
Emp. Form.:
CHNO
Mol. Mass.:
43.0247
SMILES:
[O-]N=[CH+]
Structure:
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