Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50370629
Substrate
n/a
Meas. Tech.
ChEMBL_303305 (CHEMBL840031)
Ki
3800±n/a nM
Citation
 Ilas, J; Pecar, S; Hockemeyer, J; Euler, H; Kirfel, A; Müller, CE Development of spin-labeled probes for adenosine receptors. J Med Chem 48:2108-14 (2005) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
45015.65
Organism:
Rattus norvegicus (rat)
Description:
Rat A2A receptors expressed in CHO cells.
Residue:
410
Sequence:
MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
  
Inhibitor
Name:
BDBM50370629
Synonyms:
CHEMBL607302
Type:
Small organic molecule
Emp. Form.:
C19H28N5O3
Mol. Mass.:
374.4573
SMILES:
CCCn1c2[nH]c(nc2c(=O)n(CCC)c1=O)C1=CC(C)(C)N([O])C1(C)C |t:19,^1:23|
Structure:
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