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Target
Beta-amylase
Ligand
BDBM50174836
Substrate
n/a
Meas. Tech.
ChEMBL_326643 (CHEMBL868728)
IC50
206500±n/a nM
Citation
 Seo, WD; Kim, JH; Kang, JE; Ryu, HW; Curtis-Long, MJ; Lee, HS; Yang, MS; Park, KH Sulfonamide chalcone as a new class of alpha-glucosidase inhibitors. Bioorg Med Chem Lett 15:5514-6 (2005) [PubMed]  Article 
Target
Name:
Beta-amylase
Synonyms:
AMYB | AMYB_HORVU | BMY1
Type:
PROTEIN
Mol. Mass.:
59640.69
Organism:
Hordeum vulgare
Description:
ChEMBL_326643
Residue:
535
Sequence:
MEVNVKGNYVQVYVMLPLDAVSVNNRFEKGDELRAQLRKLVEAGVDGVMVDVWWGLVEGKGPKAYDWSAYKQLFELVQKAGLKLQAIMSFHQCGGNVGDAVNIPIPQWVRDVGTRDPDIFYTDGHGTRNIEYLTLGVDNQPLFHGRSAVQMYADYMTSFRENMKDFLDAGVIVDIEVGLGPAGEMRYPSYPQSHGWSFPGIGEFICYDKYLQADFKAAAAAVGHPEWEFPNDVGQYNDTPERTQFFRDNGTYLSEKGRFFLAWYSNNLIKHGDRILDEANKVFLGYKVQLAIKISGIHWWYKVPSHAAELTAGYYNLHDRDGYRTIARMLKRHRASINFTCAEMRDLEQSSQAMSAPEELVQQVLSAGWREGLNVACENALPRYDPTAYNTILRNARPHGINQSGPPEHKLFGFTYLRLSNQLVEGQNYVNFKTFVDRMHANLPRDPYVDPMAPLPRSGPEISIEMILQAAQPKLQPFPFQEHTDLPVGPTGGMGGQAEGPTCGMGGQVKGPTGGMGGQAEDPTSGIGGELPATM
  
Inhibitor
Name:
BDBM50174836
Synonyms:
1-(3-aminophenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one | CHEMBL200185
Type:
Small organic molecule
Emp. Form.:
C15H13NO2
Mol. Mass.:
239.2692
SMILES:
Nc1cccc(c1)C(=O)\C=C\c1ccc(O)cc1
Structure:
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