Reaction Details Report a problem with these data
Target
Carbonic anhydrase
Ligand
BDBM10876
Substrate
n/a
Meas. Tech.
ChEMBL_347177 (CHEMBL862664)
Ki
870±n/a nM
Citation
 Nishimori, I; Vullo, D; Minakuchi, T; Morimoto, K; Onishi, S; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori. Bioorg Med Chem Lett 16:2182-8 (2006) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
Beta-carbonic anhydrase | CYNT_HELPY | Carbonic anhydrase 1 | cynT | hpβCA
Type:
Protein
Mol. Mass.:
25517.77
Organism:
Helicobacter pylori (strain G27)
Description:
O24855
Residue:
221
Sequence:
MKAFLGALEFQENEYEELKELYESLKTKQKPHTLFISCVDSRVVPNLITGTKPGELYVICNMGNVNPPKTSYKESLSTIASIEYAIAHVGVQNLIICGHSDCGACGSVHLIHDETTKAKTPYIANWIQFLEPVKEELKNHPQFSNHFAKRSWLTERLNARLQLNNLLSYDFIQEKASKNELKIFGWHYIIETGRIYNYNFESHFFEPIGETIKQRKSHENF
  
Inhibitor
Name:
BDBM10876
Synonyms:
4-(hydroxymethyl)benzene-1-sulfonamide | CHEMBL6919 | JMC522226 Compound 20 | JMC523116 Compound 20 | aromatic/heteroaromatic sulfonamide 21
Type:
Small organic molecule
Emp. Form.:
C7H9NO3S
Mol. Mass.:
187.216
SMILES:
NS(=O)(=O)c1ccc(CO)cc1
Structure:
Search PDB for entries with ligand similarity: