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Target
Peptide deformylase 1A, chloroplastic/mitochondrial
Ligand
BDBM50201878
Substrate
n/a
Meas. Tech.
ChEMBL_423228 (CHEMBL912247)
IC50
35000±n/a nM
Citation
 Boularot, A; Giglione, C; Petit, S; Duroc, Y; Alves de Sousa, R; Larue, V; Cresteil, T; Dardel, F; Artaud, I; Meinnel, T Discovery and refinement of a new structural class of potent peptide deformylase inhibitors. J Med Chem 50:10-20 (2007) [PubMed]  Article 
Target
Name:
Peptide deformylase 1A, chloroplastic/mitochondrial
Synonyms:
AtDEF1 | AtDEF1A | DEF1 | DEF1A_ARATH | PDF 1A | PDF1A | Peptide deformylase 1A, chloroplastic | Polypeptide deformylase
Type:
PROTEIN
Mol. Mass.:
30001.50
Organism:
Arabidopsis thaliana
Description:
ChEMBL_423228
Residue:
269
Sequence:
MGLHRDEATAMETLFRVSLRLLPVSAAVTCRSIRFPVSRPGSSHLLNRKLYNLPTSSSSSLSTKAGWLLGLGEKKKKVDLPEIVASGDPVLHEKAREVDPGEIGSERIQKIIDDMIKVMRLAPGVGLAAPQIGVPLRIIVLEDTKEYISYAPKEEILAQERRHFDLMVMVNPVLKERSNKKALFFEGCLSVDGFRAAVERYLEVVVTGYDRQGKRIEVNASGWQARILQHECDHLDGNLYVDKMVPRTFRTVDNLDLPLAEGCPKLGPQ
  
Inhibitor
Name:
BDBM50201878
Synonyms:
CHEMBL220027 | N-(1-benzenesulfonyl-5-bromo-2-methyl-1H-indol-3-ylmethyl)-N-hydroxyformamide
Type:
Small organic molecule
Emp. Form.:
C17H15BrN2O4S
Mol. Mass.:
423.281
SMILES:
Cc1c(CN(O)C=O)c2cc(Br)ccc2n1S(=O)(=O)c1ccccc1
Structure:
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