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Target
Peptide deformylase
Ligand
BDBM50201889
Substrate
n/a
Meas. Tech.
ChEMBL_423229 (CHEMBL913367)
IC50
380000±n/a nM
Citation
 Boularot, A; Giglione, C; Petit, S; Duroc, Y; Alves de Sousa, R; Larue, V; Cresteil, T; Dardel, F; Artaud, I; Meinnel, T Discovery and refinement of a new structural class of potent peptide deformylase inhibitors. J Med Chem 50:10-20 (2007) [PubMed]  Article 
Target
Name:
Peptide deformylase
Synonyms:
3.5.1.88 | BON69_24600 | BON94_18585 | D9G11_24945 | D9G11_25760 | D9J60_20755 | FORC82_p394 | PDF | Polypeptide deformylase | SAMEA3472033_04733 | def | def_2
Type:
n/a
Mol. Mass.:
16901.39
Organism:
Escherichia coli
Description:
n/a
Residue:
150
Sequence:
MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEKGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIGLRLGNGKYCTLRLFFNQV
  
Inhibitor
Name:
BDBM50201889
Synonyms:
(5-Bromo-1H-indol-3-yl)-acetic acid | 2-(5-bromo-1H-indol-3-yl)acetic acid | CHEMBL82440
Type:
Small organic molecule
Emp. Form.:
C10H8BrNO2
Mol. Mass.:
254.08
SMILES:
OC(=O)Cc1c[nH]c2ccc(Br)cc12
Structure:
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