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Target
Vitamin D3 receptor
Ligand
BDBM50205233
Substrate
n/a
Meas. Tech.
ChEMBL_428140 (CHEMBL915778)
EC50
0.0180±n/a nM
Citation
 Yamamoto, K; Inaba, Y; Yoshimoto, N; Choi, M; DeLuca, HF; Yamada, S 22-Alkyl-20-epi-1alpha,25-dihydroxyvitamin D3 compounds of superagonistic activity: syntheses, biological activities and interaction with the receptor. J Med Chem 50:932-9 (2007) [PubMed]  Article 
Target
Name:
Vitamin D3 receptor
Synonyms:
NR1I1 | VDR | VDR_BOVIN | Vitamin D receptor
Type:
PROTEIN
Mol. Mass.:
48313.44
Organism:
Bos taurus
Description:
ChEMBL_514897
Residue:
426
Sequence:
MEATAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCIDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIITTLLEAHHKTYDDTYSDFSQFRPPVRNSEDEGNRPLRSILTPSFSGNSSSSCSDHCTSSPDTMEPTSFSNQDLNEEDSDDPSVTLDLSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTPEDQIVLLKSSAIEVIMLRSNQSFTLDDDMSWTCGSPDYKYQVSDVTRAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALVEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPESSMKLTPLLFEVFGNEIS
  
Inhibitor
Name:
BDBM50205233
Synonyms:
(20S,22R)-22-methyl-1-alpha-25-dihydroxy-vitamin D3 | CHEMBL222195
Type:
Small organic molecule
Emp. Form.:
C29H48O3
Mol. Mass.:
444.6896
SMILES:
CC[C@H](CCC(C)(C)O)[C@H](C)[C@H]1CCC2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C
Structure:
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