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Target
Shikimate kinase
Ligand
BDBM50370961
Substrate
n/a
Meas. Tech.
ChEMBL_432672 (CHEMBL919243)
Ki
2190±n/a nM
Citation
 Han, C; Zhang, J; Chen, L; Chen, K; Shen, X; Jiang, H Discovery of Helicobacter pylori shikimate kinase inhibitors: bioassay and molecular modeling. Bioorg Med Chem 15:656-62 (2006) [PubMed]  Article 
Target
Name:
Shikimate kinase
Synonyms:
AROK_HELPY | SK | aroK
Type:
PROTEIN
Mol. Mass.:
18412.75
Organism:
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori)
Description:
ChEMBL_432674
Residue:
162
Sequence:
MQHLVLIGFMGSGKSSLAQELGLALKLEVLDTDMIISERVGLSVREIFEELGEDNFRMFEKNLIDELKTLKTPHVISTGGGIVMHENLKGLGTTFYLKMDFETLIKRLNQKEREKRPLLNNLTQAKELFEKRQALYEKNASFIIDARGGLNNSLKQVLQFIA
  
Inhibitor
Name:
BDBM50370961
Synonyms:
CHEMBL376902 | med.21724, Compound 110
Type:
Small organic molecule
Emp. Form.:
C21H11BrCl2N2O5
Mol. Mass.:
522.132
SMILES:
OC(=O)c1cc(Br)ccc1-c1ccc(\C=C2\C(=O)NN(C2=O)c2ccc(Cl)c(Cl)c2)o1
Structure:
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