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Target
Kappa-type opioid receptor
Ligand
BDBM50209645
Substrate
n/a
Meas. Tech.
ChEMBL_434307 (CHEMBL917886)
Ki
2010±n/a nM
Citation
 Duval, RA; Allmon, RL; Lever, JR Indium-labeled macrocyclic conjugates of naltrindole: high-affinity radioligands for in vivo studies of peripheral delta opioid receptors. J Med Chem 50:2144-56 (2007) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42744.99
Organism:
Cavia porcellus (domestic guinea pig)
Description:
P41144
Residue:
380
Sequence:
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRNVDGVNKPV
  
Inhibitor
Name:
BDBM50209645
Synonyms:
17-(cyclopropylmethyl)-6,7-didehydro-4,5alpha-epoxy-3,14-dihydroxy-1'-(10'''-[3''-propyl]-[1''',4''',7''',10'''-tetraazacyclododecane-1''',4''',7'''-triacetic acid])indolo[6,7:2',3']morphinan | CHEMBL390173
Type:
Small organic molecule
Emp. Form.:
C42H54N6O9
Mol. Mass.:
786.913
SMILES:
OC(=O)CN1CCN(CCn2c3[C@H]4Oc5c6c(C[C@H]7N(CC8CC8)CC[C@@]46[C@@]7(O)Cc3c3ccccc23)ccc5O)CCN(CC(O)=O)CCN(CC(O)=O)CC1
Structure:
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