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Target
Triosephosphate isomerase
Ligand
BDBM50167775
Substrate
n/a
Meas. Tech.
ChEMBL_440848 (CHEMBL889943)
Ki
4500±n/a nM
Citation
 Fonvielle, M; Therisod, H; Hemery, M; Therisod, M New competitive inhibitors of cytosolic (NADH-dependent) rabbit muscle glycerophosphate dehydrogenase. Bioorg Med Chem Lett 17:410-3 (2007) [PubMed]  Article 
Target
Name:
Triosephosphate isomerase
Synonyms:
TIM | TPI | TPI1 | TPIS_HUMAN | Triose-phosphate isomerase | Triosephosphate isomerase | Triosephosphate isomerase (TIM)
Type:
Enzyme
Mol. Mass.:
30788.11
Organism:
Homo sapiens (Human)
Description:
P60174
Residue:
249
Sequence:
MAPSRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ
  
Inhibitor
Name:
BDBM50167775
Synonyms:
(Z)-2-amino-2-(hydroxyimino)ethyl hydrogen phosphate | CHEMBL195976 | Phosphoric acid mono-(N-hydroxycarbamimidoylmethyl) ester
Type:
Small organic molecule
Emp. Form.:
C2H7N2O5P
Mol. Mass.:
170.0611
SMILES:
ONC(=N)COP(O)(O)=O
Structure:
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