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Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM38435
Substrate
n/a
Meas. Tech.
ChEMBL_443204 (CHEMBL893452)
Ki
610000±n/a nM
Citation
 Vidal, D; Blobel, J; Pérez, Y; Thormann, M; Pons, M Structure-based discovery of new small molecule inhibitors of low molecular weight protein tyrosine phosphatase. Eur J Med Chem 42:1102-8 (2007) [PubMed]  Article 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
ACP1 | LMW-PTP | LMW-PTPase | Low molecular weight cytosolic acid phosphatase | PPAC_BOVIN
Type:
PROTEIN
Mol. Mass.:
18055.33
Organism:
Bos taurus
Description:
ChEMBL_857178
Residue:
158
Sequence:
MAEQVTKSVLFVCLGNICRSPIAEAVFRKLVTDQNISDNWVIDSGAVSDWNVGRSPDPRAVSCLRNHGINTAHKARQVTKEDFVTFDYILCMDESNLRDLNRKSNQVKNCRAKIELLGSYDPQKQLIIEDPYYGNDADFETVYQQCVRCCRAFLEKVR
  
Inhibitor
Name:
BDBM38435
Synonyms:
9-ethyl-1-oxo-2,3,4,9-tetrahydro-1H-carbazole-6-carboxylic acid | 9-ethyl-8-keto-6,7-dihydro-5H-carbazole-3-carboxylic acid | 9-ethyl-8-oxidanylidene-6,7-dihydro-5H-carbazole-3-carboxylic acid | 9-ethyl-8-oxo-6,7-dihydro-5H-carbazole-3-carboxylic acid | MLS000061864 | SMR000070723 | cid_768661
Type:
Small organic molecule
Emp. Form.:
C15H15NO3
Mol. Mass.:
257.2845
SMILES:
CCn1c2c(CCCC2=O)c2cc(ccc12)C(O)=O
Structure:
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