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Target
5-hydroxytryptamine receptor 5A
Ligand
BDBM50371446
Substrate
n/a
Meas. Tech.
ChEMBL_463649 (CHEMBL930817)
Ki
26.5±n/a nM
Citation
 Peters, JU; Lübbers, T; Alanine, A; Kolczewski, S; Blasco, F; Steward, L Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: structure-activity relationship elucidation. Bioorg Med Chem Lett 18:256-61 (2008) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 5A
Synonyms:
5-HT-5 | 5-HT-5A | 5-hydroxytryptamine receptor 5 (5-HT5) | 5-hydroxytryptamine receptor 5A (5-HT5A) | 5HT5A_HUMAN | HTR5A | Serotonin (5-HT) receptor | Serotonin receptor 5A
Type:
Enzyme
Mol. Mass.:
40266.25
Organism:
Homo sapiens (Human)
Description:
P47898
Residue:
357
Sequence:
MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
  
Inhibitor
Name:
BDBM50371446
Synonyms:
CHEMBL439240
Type:
Small organic molecule
Emp. Form.:
C10H11Cl2N3
Mol. Mass.:
244.12
SMILES:
CCC1NC(N)=Nc2ccc(Cl)c(Cl)c12 |c:5|
Structure:
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