Reaction Details Report a problem with these data
Target
Carboxypeptidase A1
Ligand
BDBM50373035
Substrate
n/a
Meas. Tech.
ChEMBL_466366 (CHEMBL932478)
Ki
62600±n/a nM
Citation
 Wang, SH; Wang, SF; Xuan, W; Zeng, ZH; Jin, JY; Ma, J; Tian, GR Nitro as a novel zinc-binding group in the inhibition of carboxypeptidase A. Bioorg Med Chem 16:3596-601 (2008) [PubMed]  Article 
Target
Name:
Carboxypeptidase A1
Synonyms:
CBPA1_HUMAN | CPA | CPA1
Type:
PROTEIN
Mol. Mass.:
47132.61
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1496378
Residue:
419
Sequence:
MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY
  
Inhibitor
Name:
BDBM50373035
Synonyms:
CHEMBL259221
Type:
Small organic molecule
Emp. Form.:
C6H9NO4
Mol. Mass.:
159.14
SMILES:
OC(=O)C(CC=C)C[N+]([O-])=O |w:3.6|
Structure:
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