Reaction Details Report a problem with these data
Target
P2Y purinoceptor 1
Ligand
BDBM50373326
Substrate
n/a
Meas. Tech.
ChEMBL_467631 (CHEMBL930506)
Ki
0.78±n/a nM
Citation
 Pfefferkorn, JA; Choi, C; Winters, T; Kennedy, R; Chi, L; Perrin, LA; Lu, G; Ping, YW; McClanahan, T; Schroeder, R; Leininger, MT; Geyer, A; Schefzick, S; Atherton, J P2Y1 receptor antagonists as novel antithrombotic agents. Bioorg Med Chem Lett 18:3338-43 (2008) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
Enzyme
Mol. Mass.:
42090.25
Organism:
Homo sapiens (Human)
Description:
P47900
Residue:
373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEFKQNGDTSL
  
Inhibitor
Name:
BDBM50373326
Synonyms:
CHEMBL444278
Type:
Small organic molecule
Emp. Form.:
C13H18IN5O8P2
Mol. Mass.:
561.1627
SMILES:
CNc1nc(I)nc2n(cnc12)[C@H]1C[C@H](OP(O)(O)=O)[C@]2(COP(O)(O)=O)C[C@H]12
Structure:
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