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Target
Kappa-type opioid receptor
Ligand
BDBM50071370
Substrate
n/a
Meas. Tech.
ChEMBL_470454 (CHEMBL932681)
Ki
2515±n/a nM
Citation
 Ma, Z; Xu, W; Liu-Chen, LY; Lee, DY Novel coumarin glycoside and phenethyl vanillate from Notopterygium forbesii and their binding affinities for opioid and dopamine receptors. Bioorg Med Chem 16:3218-23 (2008) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM50071370
Synonyms:
(3R,8S)-falcarindiol | (3R,8S,)-heptadeca-1,9-dien-4,6-diyne-3,8-diol | (3S,8S)-falcarindiol | (Z)-(3R,8S)-Heptadeca-1,9-diene-4,6-diyne-3,8-diol | (Z)-(3S,8S)-Heptadeca-1,9-diene-4,6-diyne-3,8-diol | CHEMBL69018 | Falcarindiol | Heptadeca-1,9(Z)-diene-4,6-diyne-3,8-diol | Heptadeca-1,9-diene-4,6-diyne-3,8-diol
Type:
Small organic molecule
Emp. Form.:
C17H24O2
Mol. Mass.:
260.3713
SMILES:
CCCCCCC\C=C/[C@H](O)C#CC#C[C@H](O)C=C |r|
Structure:
Search PDB for entries with ligand similarity: