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Target
Solute carrier family 22 member 5
Ligand
BDBM50375327
Substrate
n/a
Meas. Tech.
ChEMBL_471112 (CHEMBL921265)
IC50
53000±n/a nM
Citation
 Piermatti, O; Fringuelli, F; Pochini, L; Indiveri, C; Palmerini, CA Synthesis and characterization of carnitine nitro-derivatives. Bioorg Med Chem 16:1444-51 (2008) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 5
Synonyms:
CT1 | High-affinity sodium-dependent carnitine cotransporter | OCTN2_RAT | Octn2 | Organic cation/carnitine transporter 2 | Slc22a5 | UST2r
Type:
PROTEIN
Mol. Mass.:
62570.99
Organism:
Rattus norvegicus
Description:
ChEMBL_471112
Residue:
557
Sequence:
MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLAGTPEHRCLVPHTVNLSSAWRNHSIPLETKDGRQVPQSCRRYRLATIANFSALGLEPGRDVDLEQLEQENCLDGWEYNKDVFLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQLFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRVKEAEVIIRKAAKFNGIVAPSTIFDPSELQDLNSKKPQSHHIYDLVRTRNIRIITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLAAVEVPAYVLAWLLLQHLPRRYSISAALFLGGSVLLFIQLVPSELFYLSTALVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFFPESFGAPLPDTIDQMLRVKGIKQWQIQSQTRTQKDGGESPTVLKSTAF
  
Inhibitor
Name:
BDBM50375327
Synonyms:
CHEMBL410874
Type:
Small organic molecule
Emp. Form.:
C23H45N2O7
Mol. Mass.:
461.6121
SMILES:
C[N+](C)(C)C[C@H](CC(O)=O)OC(=O)CCCCCCCCCCCCCCCO[N+]([O-])=O
Structure:
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