Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50377492
Substrate
n/a
Meas. Tech.
ChEMBL_479706 (CHEMBL933570)
Ki
1813±n/a nM
Citation
Gillespie, RJ; Cliffe, IA; Dawson, CE; Dourish, CT; Gaur, S; Giles, PR; Jordan, AM; Knight, AR; Lawrence, A; Lerpiniere, J; Misra, A; Pratt, RM; Todd, RS; Upton, R; Weiss, SM; Williamson, DS Antagonists of the human adenosine A2A receptor. Part 2: Design and synthesis of 4-arylthieno[3,2-d]pyrimidine derivatives. Bioorg Med Chem Lett 18:2920-3 (2008) [PubMed] Article
More Info.:
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE