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Target
Adenosine receptor A2b
Ligand
BDBM50262202
Substrate
n/a
Meas. Tech.
ChEMBL_509571 (CHEMBL1000457)
Ki
170±n/a nM
Citation
 Mantri, M; de Graaf, O; van Veldhoven, J; Göblyös, A; von Frijtag Drabbe Künzel, JK; Mulder-Krieger, T; Link, R; de Vries, H; Beukers, MW; Brussee, J; Ijzerman, AP 2-Amino-6-furan-2-yl-4-substituted nicotinonitriles as A2A adenosine receptor antagonists. J Med Chem 51:4449-55 (2008) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50262202
Synonyms:
2-Amino-6-furan-2-yl-4-phenyl-nicotinonitrile | CHEMBL468370
Type:
Small organic molecule
Emp. Form.:
C16H11N3O
Mol. Mass.:
261.278
SMILES:
Nc1nc(cc(-c2ccccc2)c1C#N)-c1ccco1
Structure:
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