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Target
Beta-ketoacyl-[acyl-carrier-protein] synthase III
Ligand
BDBM50245877
Substrate
n/a
Meas. Tech.
ChEMBL_559689 (CHEMBL1010087)
IC50
278.7±n/a nM
Citation
 Alhamadsheh, MM; Waters, NC; Sachdeva, S; Lee, P; Reynolds, KA Synthesis and biological evaluation of novel sulfonyl-naphthalene-1,4-diols as FabH inhibitors. Bioorg Med Chem Lett 18:6402-5 (2008) [PubMed]  Article 
Target
Name:
Beta-ketoacyl-[acyl-carrier-protein] synthase III
Synonyms:
Beta-ketoacyl-ACP-synthase III
Type:
PROTEIN
Mol. Mass.:
42334.64
Organism:
Plasmodium falciparum
Description:
ChEMBL_559689
Residue:
371
Sequence:
MFLYFITYLCIFHNNIYSVELIKNNKYNFINNVHNIKYRTKIRAIYGKTGGKIIGHGHSYPSTEIYNDELKKYVDTNDEWIRTRTGIKKRRILKRDENISMLQIDSATQALETSCLKPSDIDMVINASSTPQNLFGDANNISNKIGCKNSVNMDLTAACTGFIFAFVTAYNFLNRYKNILIVGSDALSNFVDWRDRNTCVLFGDAAGAVVLQRTEEKEENKIFNYYLGSDSELNDLLTINFDHDKYNLDKPNVNKYGKLYMNGKEVFKYTISNIPKILKKAIQHSNINIEDINYFIFHQANIRIIETVAKNLNIPMSKVLVNLDEYANTSAASIPLCFSENIKNGKIKTNDIICMCGFGAGMSYGCVILKY
  
Inhibitor
Name:
BDBM50245877
Synonyms:
2-(phenylsulfonyl)naphthalene-1,4-diol | CHEMBL462205
Type:
Small organic molecule
Emp. Form.:
C16H12O4S
Mol. Mass.:
300.329
SMILES:
Oc1cc(c(O)c2ccccc12)S(=O)(=O)c1ccccc1
Structure:
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