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Target
Adenosine receptor A2b
Ligand
BDBM50013721
Substrate
n/a
Meas. Tech.
ChEMBL_566531 (CHEMBL955117)
Ki
>30000±n/a nM
Citation
 Lambertucci, C; Antonini, I; Buccioni, M; Dal Ben, D; Kachare, DD; Volpini, R; Klotz, KN; Cristalli, G 8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A2A and A2B receptors ligands. Bioorg Med Chem 17:2812-22 (2009) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50013721
Synonyms:
8-Br-adenine | 8-Bromo-9H-purin-6-ylamine0.9M HCl | CHEMBL65747
Type:
Small organic molecule
Emp. Form.:
C5H4BrN5
Mol. Mass.:
214.023
SMILES:
Nc1ncnc2nc(Br)[nH]c12
Structure:
Search PDB for entries with ligand similarity: