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Target
Papain
Ligand
BDBM50249353
Substrate
n/a
Meas. Tech.
ChEMBL_499481 (CHEMBL1021973)
IC50
693100±n/a nM
Citation
 Martins, FT; Assis, DM; Dos Santos, MH; Camps, I; Veloso, MP; Juliano, MA; Alves, LC; Doriguetto, AC Natural polyprenylated benzophenones inhibiting cysteine and serine proteases. Eur J Med Chem 44:1230-9 (2009) [PubMed]  Article 
Target
Name:
Papain
Synonyms:
Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I
Type:
Enzyme
Mol. Mass.:
38923.01
Organism:
Carica papaya
Description:
Papain was purchased from Sigma, Germany.
Residue:
345
Sequence:
MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNEYSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYGPNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
  
Inhibitor
Name:
BDBM50249353
Synonyms:
1,1,3-trihydroxybenzophenone | 2,2',4-trihydroxybenzophenone | CHEMBL470701 | Polyhydroxy benzophenone, 13
Type:
Small organic molecule
Emp. Form.:
C13H10O4
Mol. Mass.:
230.2161
SMILES:
Oc1ccc(C(=O)c2ccccc2O)c(O)c1
Structure:
Search PDB for entries with ligand similarity: