Reaction Details Report a problem with these data
Target
Transcriptional activator protein TraR
Ligand
BDBM50300130
Substrate
n/a
Meas. Tech.
ChEMBL_593847 (CHEMBL1049319)
IC50
1000±n/a nM
Citation
 Ahumedo, M; Díaz, A; Vivas-Reyes, R Theoretical and structural analysis of the active site of the transcriptional regulators LasR and TraR, using molecular docking methodology for identifying potential analogues of acyl homoserine lactones (AHLs) with anti-quorum sensing activity. Eur J Med Chem 45:608-15 (2010) [PubMed]  Article 
Target
Name:
Transcriptional activator protein TraR
Synonyms:
TRAR_RHIRD | traR
Type:
PROTEIN
Mol. Mass.:
26741.83
Organism:
Rhizobium radiobacter
Description:
ChEMBL_765233
Residue:
234
Sequence:
MQHWLDKLTDLAAIEGDECILKTGLADIADHFGFTGYAYLHIQHRHITAVTNYHRQWQSTYFDKKFEALDPVVKRARSRKHIFTWSGEHERPTLSKDERAFYDHASDFGIRSGITIPIKTANGFMSMFTMASDKPVIDLDREIDAVAAAATIGQIHARISFLRTTPTAEDAAWLDPKEATYLRWIAVGKTMEEIADVEGVKYNSVRVKLREAMKRFDVRSKAHLTALAIRRKLI
  
Inhibitor
Name:
BDBM50300130
Synonyms:
CHEMBL573745 | N-(2-cyclopentene-1-acetanoyl)-L-homoserine lactone
Type:
Small organic molecule
Emp. Form.:
C11H15NO3
Mol. Mass.:
209.2417
SMILES:
O=C(CC1CCC=C1)N[C@H]1CCOC1=O |r,c:6|
Structure:
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