Reaction Details Report a problem with these data
Target
Dihydropteroate synthase
Ligand
BDBM50378559
Substrate
n/a
Meas. Tech.
ChEMBL_595738 (CHEMBL1045261)
IC50
212600±n/a nM
Citation
 Hevener, KE; Yun, MK; Qi, J; Kerr, ID; Babaoglu, K; Hurdle, JG; Balakrishna, K; White, SW; Lee, RE Structural studies of pterin-based inhibitors of dihydropteroate synthase. J Med Chem 53:166-77 (2010) [PubMed]  Article 
Target
Name:
Dihydropteroate synthase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
30967.84
Organism:
Bacillus anthracis
Description:
ChEMBL_595739
Residue:
280
Sequence:
MCSLKWDYDLRCGEYTLNLNEKTLIMGILNVTPDSFSDGGSYNEVDAAVRHAKEMRDEGAHIIDIGGESTRPGFAKVSVEEEIKRVVPMIQAVSKEVKLPISIDTYKAEVAKQAIEAGAHIINDIWGAKAEPKIAEVAAHYDVPIILMHNRDNMNYRNLMADMIADLYDSIKIAKDAGVRDENIILDPGIGFAKTPEQNLEAMRNLEQLNVLGYPVLLGTSRKSFIGHVLDLPVEERLEGTGATVCLGIEKGCEFVRVHDVKEMSRMAKMMDAMIGKGVK
  
Inhibitor
Name:
BDBM50378559
Synonyms:
CHEMBL344471
Type:
Small organic molecule
Emp. Form.:
C7H11N5O
Mol. Mass.:
181.1951
SMILES:
CC1CNc2nc(N)[nH]c(=O)c2N1
Structure:
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