Reaction Details Report a problem with these data
Target
Dihydropteroate synthase
Ligand
BDBM50378554
Substrate
n/a
Meas. Tech.
ChEMBL_595739 (CHEMBL1045262)
Kd
5260±n/a nM
Citation
 Hevener, KE; Yun, MK; Qi, J; Kerr, ID; Babaoglu, K; Hurdle, JG; Balakrishna, K; White, SW; Lee, RE Structural studies of pterin-based inhibitors of dihydropteroate synthase. J Med Chem 53:166-77 (2010) [PubMed]  Article 
Target
Name:
Dihydropteroate synthase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
30967.84
Organism:
Bacillus anthracis
Description:
ChEMBL_595739
Residue:
280
Sequence:
MCSLKWDYDLRCGEYTLNLNEKTLIMGILNVTPDSFSDGGSYNEVDAAVRHAKEMRDEGAHIIDIGGESTRPGFAKVSVEEEIKRVVPMIQAVSKEVKLPISIDTYKAEVAKQAIEAGAHIINDIWGAKAEPKIAEVAAHYDVPIILMHNRDNMNYRNLMADMIADLYDSIKIAKDAGVRDENIILDPGIGFAKTPEQNLEAMRNLEQLNVLGYPVLLGTSRKSFIGHVLDLPVEERLEGTGATVCLGIEKGCEFVRVHDVKEMSRMAKMMDAMIGKGVK
  
Inhibitor
Name:
BDBM50378554
Synonyms:
CHEMBL577547
Type:
Small organic molecule
Emp. Form.:
C8H9N5O3
Mol. Mass.:
223.1888
SMILES:
CN1CC(=Nc2c1nc(N)[nH]c2=O)C(O)=O |c:3|
Structure:
Search PDB for entries with ligand similarity: