Reaction Details Report a problem with these data
Target
Dihydropteroate synthase
Ligand
BDBM50145829
Substrate
n/a
Meas. Tech.
ChEMBL_595739 (CHEMBL1045262)
Kd
5620±n/a nM
Citation
 Hevener, KE; Yun, MK; Qi, J; Kerr, ID; Babaoglu, K; Hurdle, JG; Balakrishna, K; White, SW; Lee, RE Structural studies of pterin-based inhibitors of dihydropteroate synthase. J Med Chem 53:166-77 (2010) [PubMed]  Article 
Target
Name:
Dihydropteroate synthase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
30967.84
Organism:
Bacillus anthracis
Description:
ChEMBL_595739
Residue:
280
Sequence:
MCSLKWDYDLRCGEYTLNLNEKTLIMGILNVTPDSFSDGGSYNEVDAAVRHAKEMRDEGAHIIDIGGESTRPGFAKVSVEEEIKRVVPMIQAVSKEVKLPISIDTYKAEVAKQAIEAGAHIINDIWGAKAEPKIAEVAAHYDVPIILMHNRDNMNYRNLMADMIADLYDSIKIAKDAGVRDENIILDPGIGFAKTPEQNLEAMRNLEQLNVLGYPVLLGTSRKSFIGHVLDLPVEERLEGTGATVCLGIEKGCEFVRVHDVKEMSRMAKMMDAMIGKGVK
  
Inhibitor
Name:
BDBM50145829
Synonyms:
4-Aminobenzoesaeure | 4-aminobenzoic acid | CHEMBL542 | PABA | p-Aminobenzoesaeure | p-aminobenzoic acid | para-aminobenzoic acid
Type:
Small organic molecule
Emp. Form.:
C7H7NO2
Mol. Mass.:
137.136
SMILES:
Nc1ccc(cc1)C(O)=O
Structure:
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