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Target
P2Y purinoceptor 6
Ligand
BDBM50306710
Substrate
n/a
Meas. Tech.
ChEMBL_611870 (CHEMBL1070825)
EC50
13±n/a nM
Citation
 Ginsburg-Shmuel, T; Haas, M; Schumann, M; Reiser, G; Kalid, O; Stern, N; Fischer, B 5-OMe-UDP is a potent and selective P2Y(6)-receptor agonist. J Med Chem 53:1673-85 (2010) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 6
Synonyms:
P2RY6 | P2RY6_HUMAN | P2Y purinoceptor 6 | P2Y6 | Pyrimidinergic receptor P2Y6
Type:
PROTEIN
Mol. Mass.:
36452.29
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1511151
Residue:
328
Sequence:
MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAKWQRQGR
  
Inhibitor
Name:
BDBM50306710
Synonyms:
((2R,3S,4R,5R)-3,4-dihydroxy-5-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl trihydrogen diphosphate | CHEMBL1094759 | CHEMBL590494
Type:
Small organic molecule
Emp. Form.:
C9H13IN2O12P2
Mol. Mass.:
530.0577
SMILES:
O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)n1cc(I)c(=O)[nH]c1=O |r|
Structure:
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