Reaction Details Report a problem with these data
Target
Adenosine 5'-monophosphoramidase HINT1
Ligand
BDBM22579
Substrate
n/a
Meas. Tech.
ChEMBL_657461 (CHEMBL1246573)
Kd
1100000±n/a nM
Citation
 Bai, G; Feng, B; Wang, JB; Pozharski, E; Shapiro, M Studies on ligand binding to histidine triad nucleotide binding protein 1. Bioorg Med Chem 18:6756-62 (2010) [PubMed]  Article 
Target
Name:
Adenosine 5'-monophosphoramidase HINT1
Synonyms:
HINT1_RAT | Hint1 | Hint | Pkci1 | Protein kinase C-interacting protein 1
Type:
PROTEIN
Mol. Mass.:
13778.26
Organism:
Rat
Description:
ChEMBL_657463
Residue:
126
Sequence:
MADEIAKAQVAQPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVADDDDESLLGHLMIVGKKCAADLGLKRGYRMVVNEGADGGQSVYHIHLHVLGGRQMNWPPG
  
Inhibitor
Name:
BDBM22579
Synonyms:
Aminoimidazole-4-carboxamide ribonucleotide | CHEMBL483849 | ZMP | {[(2R,3S,4R,5R)-5-(5-amino-4-carbamoyl-1H-imidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid | AICAR
Type:
Nucleoside or nucleotide
Emp. Form.:
C9H15N4O8P
Mol. Mass.:
338.06
SMILES:
c1nc(c(n1[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O)N)C(=O)N
Structure:
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