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Target
Motilin receptor
Ligand
BDBM50327556
Substrate
n/a
Meas. Tech.
ChEMBL_664665 (CHEMBL1260551)
EC50
700±n/a nM
Citation
 Liu, Y; Li, Y; Chen, Y; Zheng, H; Claypool, M; Myles, DC; Carreras, CW 9-Dihydroerythromycins as non-antibiotic motilin receptor agonists. Bioorg Med Chem Lett 20:5658-61 (2010) [PubMed]  Article 
Target
Name:
Motilin receptor
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
43771.25
Organism:
Oryctolagus cuniculus
Description:
n/a
Residue:
400
Sequence:
MGSPWNGSDGPEDAREPPWAALPPCDERRCSPFPLGTLVPVTAVCLGLFAVGVSGNVVTVLLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGQLLCRLSLYVGEGCTYASLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAALWAVALLSAGPFFFLVGVEQDPAVFAAPDRNGTVPLDPSSPAPASPPSGPGAEAAALFSRECRPSRAQLGLLRVMLWVTTAYFFLPFLCLSILYGLIARQLWRGRGPLRGPAATGRERGHRQTVRVLLVVVLAFIVCWLPFHVGRIIYINTQDSRMMYFSQYFNIVALQLFYLSASINPILYNLISKKYRAAARRLLRESRAGPSGVCGSRGPEQDVAGDTGGDTAGCTETSANTKTAA
  
Inhibitor
Name:
BDBM50327556
Synonyms:
(3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-14-ethyl-7,10,12,13-tetrahydroxy-6-((2S,3R,4S,6R)-3-hydroxy-4-((3-hydroxypropyl)(methyl)amino)-6-methyltetrahydro-2H-pyran-2-yloxy)-4-((2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yloxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one | CHEMBL1256544
Type:
Small organic molecule
Emp. Form.:
C39H73NO14
Mol. Mass.:
779.9952
SMILES:
CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)CCCO)[C@](C)(O)C[C@@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@]1(C)O |r|
Structure:
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