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Target
ETS translocation variant 1
Ligand
BDBM50379275
Substrate
n/a
Meas. Tech.
ChEMBL_811272 (CHEMBL2015224)
Kd
17400±n/a nM
Citation
 Kemp, MM; Weïwer, M; Koehler, AN Unbiased binding assays for discovering small-molecule probes and drugs. Bioorg Med Chem 20:1979-89 (2012) [PubMed]  Article 
Target
Name:
ETS translocation variant 1
Synonyms:
ER81 | ETV1 | ETV1_HUMAN | Ets-related protein 81
Type:
PROTEIN
Mol. Mass.:
55125.21
Organism:
Homo sapiens (Human)
Description:
ChEMBL_811272
Residue:
477
Sequence:
MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
  
Inhibitor
Name:
BDBM50379275
Synonyms:
CHEMBL2011500
Type:
Small organic molecule
Emp. Form.:
C17H13Cl2NO4
Mol. Mass.:
366.195
SMILES:
COc1ccc(cc1)C(=O)CC1(O)C(=O)Nc2c1c(Cl)ccc2Cl
Structure:
Search PDB for entries with ligand similarity: