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Target
Membrane-bound lytic murein transglycosylase B
Ligand
BDBM50386412
Substrate
n/a
Meas. Tech.
ChEMBL_826832 (CHEMBL2051549)
Kd
174000±n/a nM
Citation
 Yamaguchi, T; Blázquez, B; Hesek, D; Lee, M; Llarrull, LI; Boggess, B; Oliver, AG; Fisher, JF; Mobashery, S Inhibitors for Bacterial Cell-Wall Recycling. ACS Med Chem Lett 3:238-242 (2012) [PubMed]  Article 
Target
Name:
Membrane-bound lytic murein transglycosylase B
Synonyms:
35 kDa soluble lytic transglycosylase | 4.2.2.n1 | JW2671 | MLTB_ECOLI | Murein hydrolase B | Slt35 | mltB
Type:
PROTEIN
Mol. Mass.:
40263.83
Organism:
Escherichia coli (strain K12)
Description:
ChEMBL_826832
Residue:
361
Sequence:
MFKRRYVTLLPLFVLLAACSSKPKPTETDTTTGTPSGGFLLEPQHNVMQMGGDFANNPNAQQFIDKMVNKHGFDRQQLQEILSQAKRLDSVLRLMDNQAPTTSVKPPSGPNGAWLRYRKKFITPDNVQNGVVFWNQYEDALNRAWQVYGVPPEIIVGIIGVETRWGRVMGKTRILDALATLSFNYPRRAEYFSGELETFLLMARDEQDDPLNLKGSFAGAMGYGQFMPSSYKQYAVDFSGDGHINLWDPVDAIGSVANYFKAHGWVKGDQVAVMANGQAPGLPNGFKTKYSISQLAAAGLTPQQPLGNHQQASLLRLDVGTGYQYWYGLPNFYTITRYNHSTHYAMAVWQLGQAVALARVQ
  
Inhibitor
Name:
BDBM50386412
Synonyms:
CHEMBL2047302
Type:
Small organic molecule
Emp. Form.:
C8H16N2O4
Mol. Mass.:
204.2236
SMILES:
CC(=O)N[C@H]1CN[C@H](CO)[C@@H](O)[C@@H]1O |r|
Structure:
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