Reaction Details Report a problem with these data
Target
Beta-hexosaminidase
Ligand
BDBM50386412
Substrate
n/a
Meas. Tech.
ChEMBL_826893 (CHEMBL2051708)
Ki
300±n/a nM
Citation
 Yamaguchi, T; Blázquez, B; Hesek, D; Lee, M; Llarrull, LI; Boggess, B; Oliver, AG; Fisher, JF; Mobashery, S Inhibitors for Bacterial Cell-Wall Recycling. ACS Med Chem Lett 3:238-242 (2012) [PubMed]  Article 
Target
Name:
Beta-hexosaminidase
Synonyms:
Beta-N-acetylhexosaminidase | N-acetyl-beta-glucosaminidase | NAGZ_PSEAE | nagZ
Type:
PROTEIN
Mol. Mass.:
36098.90
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_826893
Residue:
332
Sequence:
MQGSLMLDIGGTWLTAEDRQILRHPEVGGLIIFARNIEHPAQVRELCAAIRAIRPDLLLAVDQEGGRVQRLRQGFVRLPAMRAIADNPNAEELAEHCGWLMATEVQAVGLDLSFAPVLDLDHQRSAVVGSRAFEGDPERAALLAGAFIRGMHAAGMAATGKHFPGHGWAEADSHVAIPEDARSLEEIRRSDLVPFARLAGQLDALMPAHVIYPQVDPQPAGFSRRWLQEILRGELKFDGVIFSDDLSMAGAHVVGDAASRIEAALAAGCDMGLVCNDRASAELALAALQRLKVTPPSRLQRMRGKGYANTDYRQQPRWLEALSALRAAQLID
  
Inhibitor
Name:
BDBM50386412
Synonyms:
CHEMBL2047302
Type:
Small organic molecule
Emp. Form.:
C8H16N2O4
Mol. Mass.:
204.2236
SMILES:
CC(=O)N[C@H]1CN[C@H](CO)[C@@H](O)[C@@H]1O |r|
Structure:
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